After finding the density altitude with the E6-B you can find the charts for takeoff roll in your POH, if one is available. More accurate is taking off with yourself and ten gallons fuel and work up from there. Remember the temperature rise during the day increases the density altitude. With this technique, you automatically add in all the variables: runway condition, obstructions, technique, wind, engine performance, etc.
As far as technique when very heavy and very high density altitude:
1. Always lean prior to takeoff.
2. The nose wheel creates lots of drag. Get it off as soon as possible.
3. The main wheels create lots of drag. Get them off as soon as possible.
4. Airplanes accelerate faster level than pitched up. Push over into low ground effect as soon as the mains come off.
5. The fastest speed possible (other things being equal) is in the lowest ground effect possible. Six inches is good.
6. Don't try to go over anything you can go around in low ground effect. Up to 15 degree turns are comfortable in ground effect. Keep wing level with aileron while making all turns with rudder.
7. Down drainage is not only a viable option, sometimes it is the only option.
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