As I've said elsewhere, I don't think an after market turbo makes good sense. A factory turbo, if the airplane NEEDS the extra power, makes a little more sense. But with the turbo often comes extra maintenance, shortened engine life, and thereby extra cost. While my 180hp normally aspirated Lycoming is breathing hard at the DAs involved in the high country, a stock 182 is different--depending on loading, it can do quite well.
At most high country airfields, FWIW, you'll find the majority of airplanes are normally aspirated.
So your friend needs to consider how he's going to use the airplane. If most of his flights are 2 up and not fully loaded, a normally aspirated 182 will work just fine out of Telluride. If he does fill it to gross, then it'll be pretty anemic; if that's only occasionally, then no big deal as long as he plans for it. But if his regular every day flights are fully loaded, then perhaps a factory turbo makes sense, with the recognition that it will require increased maintenance.
Cary