I have very little experience flying behind 2 stroke engines. But used to buy broken dirt bikes, fix them, ride them (enduro and track) and sell them when they ran well and looked pretty. Can't recall how many times the bikes quit on me going steep climbs, always fouled spark plug. Usually rode 125s, which were small for the climbs (TORR usually).
Once I switched to full synthetic 2-stroke oil, I had no more issues, never fouled a spark plug again, on 125, or on the occasional 250 I sometimes owned/rode. I started using the same on the PWC (Kawasaki 550sx and Yamaha FX-1 and later a Superjet), same thing, not a problem, except on one 1984 550 that broke in 2015 with unknown hours, care or history. I used it on the chain saws (lots of trees around here, so they work every day), weed eaters, water pumps for sprayers, etc.
If I ever bought a 2-stroke airplane/paraglider/trike/etc. I would do the same. Right now I put 40:1 ratio on everything for simplicity, maybe for a flying machine that would need to be adjusted. I mainly used Amsoil Interceptor, and now that I am in Argentina I use AMA Gold Fire. I tried other brands with similar results, Motul, Repsol, and Maxima. As Maxima has castor oil in it so the exhaust smells a lot better. You can tell on a race when the guy ahead has castor oil in the mix. I've mixed Amsoil and Castor oil myself. When I opened the engines, I found no difference between brands, they all looked good as long as they were full synthetic, or mixed with a little bit of castor oil.
Just my 2 cents on the topic.

I run Amsoil Interceptor at 40:1 with 100LL in my Rotax 582. 140 hours since I started doing that, no issues.