Hi Wes,
All good questions, but unfortunately this one, like the last one could have no other short answer other than 'it depends'.
Over in Marty's country, where it's 90% corn, beans and fungicide, those days may not be over, but it is certainly possible to just jump right in an airplane, with minimal training and go to work… After all, by that point you should at least be able to keep from running in to things.
The operator who likely has been working the region for years and has a vested interest in keeping it viable for years to come will manage which jobs go to whom, he will also likely know that up till now an
all up gross wt airplane is heavy to you (let alone the typical
Early Thrush load governed under CAM8 that would essentially be
5 times the modern equivalent of max gross in the same airframe

…) consequently he will load you accordingly, and getting in and going should be no big deal.
I have known pilots with minimum time to earn the CPL who have started ag careers, and done well. I have know corporate / military / ATP types who went right in to turbines and started great careers… it is doable that way.
Conversely, there are seats that are just going to take that much time to learn… and if you want to start in one of those regions, starting without a major chunk of insight will be virtually impossible.
Here's an example,
In our region, pretty much everything is based on a 40 acre block.
Conveniently, as per normal practices we size our aircraft to make this one load.
The bread and butter of the region is produce… to keep it simple let's just call it salad… and for this exercise we'll just pick lettuce…
Lettuce like every other commodity goes up and down, but this season it seemed to hover around $20/box. Times that by 1000 boxes/acre and then 40 acres…. per load… What is that .8 Mill? almost a cool million
Average me out at 20 loads a night, and then figure out how much the value of one nights crop is that I am charged with spraying… Let's call that 20 cool million
Now back out the $300K (yes, that's three hundred thousand) the insurance company is going to hand you
when you screw the pooch (notice I did not say
if you screw the pooch). Kinda falls short of covering the not so cool lettuce
Now back to Marty's country… the only real way to screw the pooch on the crop is drift a herbicide on it and kill it… so as a NFG you'r not likely to be tasked with that job… That's an over simplification, because there are actually many other ways to get a crop red tagged, but it's just not that common. Back over in people crop land, herbicide is the least of your worries, because that's a no - brained. What bites people here is spraying a totally benign chemical on a block of produce, right next to another block of produce that it's not registered on. It might not even harm that crop, but when it turns up hot when they check it at the cooler, you just bought it…

In fact, on that end it could even be a totally registered and legal chemical, but drifted onto a field that is farther along and consequently it is inside the labeled days to harvest (harvest interval) in other words , good crop, good chemical, bad timing… you bought it.
Incidentally, one of the reasons I said herbicide was a no-brainers is because it's so quick to tell on you… you're going to know tomorrow if youu screwed the pooch today. These other examples may not show up for months

Just imagine how many pooches the new guy could screw before the first ones started turning up hot
So to draw a conclusion from all this, what you're asking is, will todays operator gamble $19.5 million a night of his own hard earned cash on a new pilot that flies really well but has never sprayed a load in his life. because there's a pilot shortage? … Don't see it ever happening that way in this neck of the woods…
Take care, Rob