Running the engine occasionally over the last 10 or 12 years didn't do it any good. That was the case with my LRB, which threw a rod after I'd had her for 15 hours. Often the potential engine problems won't show up on any pre-buy, but you can just about count on problems from lack of use. So that needs to be taken into account as to whether the price is appropriate--you may be in the market for a new engine a whole lot sooner than you would like.
The panel on this one is OK, but certainly not current avionics.
The biggest issue with any 182, especially pre-1970, is a relatively weak nose gear/firewall. Even later models have some issues with it, but the pre-1970 models are worse. That means that any hard landing is likely to have dinged the firewall. There are 2 issues there, did it happen, and was it properly repaired.
I'm involved in litigation right now in which the airplane, a 67 Skylane, had at least 2 significant prangs when it was near new resulting in 2 NTSB reports with the possibility of another accident which didn't get to the NTSB, and at some point the firewall was improperly replaced. The buyer was fooled by a nice paint job and nice interior, decided not to do a pre-buy, didn't recognize the unairworthy repairs (some were, of course, covered over by the nice paint), and basically was cheated. My litigation is between him and the mechanic he hired to make it airworthy--their dispute is over the cost and length of time necessary to properly repair it.
If the airplane you're looking at only has standard tanks, you're basically looking at a 3 hour range plus reserves. Not sure that's bad (I have a hard time flying longer than that, although my airplane can), but it's a factor. Earlier 182s don't have the width of later ones, but they're still wider than a 172, so that's not a big deal. They don't have the load carrying capacity of newer ones, but still plenty for most people's needs.
I have the Madras tips--the previous owner had installed them. They look STOL-ish, which I suppose is cool. They do provide better low airspeed control, but they also add drag. I figure they lopped off maybe 4-5 knots at cruise, which I got back by having flap gap seals installed. They do interfere a little with visibility, and they are head knockers. But I elected to leave them on.
If indeed the airplane passes a thorough pre-buy, I think the biggest issue will be the engine, due to its low hours SMOH over such a long period of time. Second for me would be the dated avionics, which would be expensive to bring up to date.
Cary