I haven't flown a Cherokee into any back country areas, but every time I fly to Marble, CO, there are a couple. I think the smallest I've seen was a 180 hp version, though. Like the old silly discussion about high wing vs. low wing, the only real difference is that on one, the wing is on top and on the other, the wing is on the bottom. They fly the same, for all practical purposes.
If you spend any time on this site, you'll see contributions by Piper Painter, who flies a red Mooney into places some folks won't fly anything into. So low wing isn't by any means a restriction--
as long as the strip is wide enough that any scrub brush to the sides doesn't clip a wingtip. Airfield elevation and density altitude are the biggest issues when flying lower powered airplanes, regardless of the wing location. A 150 hp Cherokee won't perform as well as a 180 hp (or more) version--same rule applies to a 145/150/160 hp 172 vs. a 180 hp 172. If you're going into any higher elevation strip, or into the mountains (even those bumps that pass for mountains in the East), you have to be pretty careful. You can't rely on power to get you out of trouble, because you just don't have much excess power to play with. You must rely on piloting technique, things like using low ground effect to obtain necessary climb speed, and the orographic effects of wind, etc., and good judgment, such as taking off earlier or later in the day when it's cooler.
The only other thing that I'd mention is that many Cherokee pilots tend to land flat. While the Cherokee nose gear is pretty sturdy, it won't take too many nose-heavy landings to break it. So practice so that all of your landings are definitely on the mains. Here's a video of what happens if you don't:
Cary